Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion
Sign Up to like & getrecommendations! Published in 2022 at "Hematology"
DOI: 10.1080/16078454.2022.2140992
Abstract: ABSTRACT Aim This study aims to explore the expression and role of CD72 in B lymphocytes in immune thrombocytopenic purpura (ITP). Methods The expression level of CD72 in B lymphocytes was detected by flow cytometry… read more here.
Keywords: antibody; itp patients; cell proliferation; cd72 ... See more keywords
In Vitro-Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-130938
Abstract: Introduction: B-cell acute lymphoblastic leukemia (B-ALL) patients that harbor rearrangements of the Mixed-lineage leukemia gene (MLLr; also known as KMT2Ar) have particularly dismal clinical outcomes. Although CAR T immunotherapies targeting CD19 have shown impressive responses… read more here.
Keywords: cd72; mllr; nanobody; expression ... See more keywords