Bispecific antibody CD73xEpCAM selectively inhibits the adenosine-mediated immunosuppressive activity of carcinoma-derived extracellular vesicles.
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DOI: 10.1016/j.canlet.2021.08.037
Abstract: Tumor-derived extracellular vesicles (EVs) carry potent immunosuppressive factors that affect the antitumor activities of immune cells. A significant part of the immunoinhibitory activity of EVs is attributable to CD73, a GPI-anchored ecto-5'-nucleotidase involved in the… read more here.
Keywords: extracellular vesicles; derived extracellular; cd73xepcam; bispecific antibody ... See more keywords