Significance of IL-17A-producing CD8+CD103+ skin resident memory T cells in psoriasis lesion and their possible relationship to clinical course.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.06.002
Abstract: BACKGROUND A number of studies have shown the relationship between the pathogenesis of psoriasis and skin resident memory T (TRM) cells. OBJECTIVE To investigate the cytokine profile of TRM cells from skin lesions of psoriasis… read more here.
Keywords: psoriasis; cd103; trm cells; cd8 cd103 ... See more keywords
CD8+CD103+ iTregs inhibit the progression of lupus nephritis by attenuating glomerular endothelial cell injury.
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology"
DOI: 10.1093/rheumatology/kez112
Abstract: OBJECTIVES We previously reported that ex vivo TGF-β and IL-2-induced CD8+CD103+ regulatory T cells (CD8+CD103+ iTregs) displayed similar immunosuppressive effect and therapeutic function on lupus mice nephritis to that of CD4+Foxp3+ Tregs. In view of… read more here.
Keywords: injury; cd103 itregs; microscopy; cd8 cd103 ... See more keywords
CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-001807
Abstract: Background Tumor infiltrating lymphocytes play a key role in antitumor responses; however, while several memory T-cell subtypes have been reported in inflammatory and neoplastic conditions, the proportional representation of the different subsets of memory T… read more here.
Keywords: microscopy; cd8 cd103; cancer; cell ... See more keywords
Cancer stem-like cells evade CD8+CD103+ tumor-resident memory T (TRM) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-004527
Abstract: Background Cancer stem cells (CSC) define a population of rare malignant cells endowed with ‘stemness’ properties, such as self-renewing, multipotency and tumorigenicity. They are responsible for tumor initiation and progression, and could be associated with… read more here.
Keywords: cell; trm; cd8 cd103; tumor ... See more keywords
Tumor infiltrating CD8/CD103/TIM-3-expressing lymphocytes in epithelial ovarian cancer co-express CXCL13 and associate with improved survival
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1031746
Abstract: Reactivation of tumor infiltrating T lymphocytes (TILs) with immune checkpoint inhibitors or co-stimulators has proven to be an effective anti-cancer strategy for a broad range of malignancies. However, epithelial ovarian cancer (EOC) remains largely refractory… read more here.
Keywords: epithelial ovarian; tumor infiltrating; ovarian cancer; cd8 cd103 ... See more keywords