CD8+CD28+/CD8+CD28- T cell equilibrium can predict the active stage for patients with inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2017.03.009
Abstract: BACKGROUND/AIM The balance of blood CD8+CD28+/CD8+CD28- T cells has been verified to be vital for patients with ulcerative colitis (UC), but their role in inflammatory bowel disease (IBD) remains unknown. This investigation aimed to evaluate… read more here.
Keywords: cd28 cell; cd28 cd8; cd8 cd28; cd28 ... See more keywords
Circulating CD8+CD28- suppressor T cells tied to poorer prognosis among metastatic breast cancer patients receiving adoptive T-cell therapy: A cohort study.
Sign Up to like & getrecommendations! Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2017.08.018
Abstract: BACKGROUND AIMS This study aimed to determine the prognostic value of circulating CD8+CD28- T lymphocytes among breast cancer patients treated with adoptive T-lymphocyte immunotherapy after chemotherapy. METHODS Two hundred and thirty-two breast cancer patients underwent… read more here.
Keywords: breast cancer; cd28; circulating cd8; proportion ... See more keywords
CD8+CD28-T-cells: Key cytotoxic players impacting disease pathogenesis in chronic HBV infection.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical science"
DOI: 10.1042/cs20190369
Abstract: During chronic hepatitis B (CHB), CD8+T-cells downregulate CD28, the primary costimulation molecule for T-cell activation. Diverse functional attributes of CD8+CD28-T-cells are suggested in various disease contexts. The present study aimed to characterize CD8+CD28-T-cells in different… read more here.
Keywords: cd28; cell; cd28 cells; hbv ... See more keywords
Imbalance between CD8+CD28+ and CD8+CD28– T-cell subsets and its clinical significance in patients with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2019 at "Lupus"
DOI: 10.1177/0961203319867130
Abstract: Objective The aim of this study was to evaluate the changes in CD8+CD28–/CD8+CD28+ T-cell subset balance and in the CD8+CD28– Treg cell number and function in patients with systemic lupus erythematosus (SLE). Methods Cell isolation… read more here.
Keywords: cd28 cell; cell subset; cd8 cd28; cd28 ... See more keywords
Correlation of CD28 expression on CD8+ T cells with prognosis in advanced lung adenocarcinomas and squamous cell carcinomas.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e14185
Abstract: e14185 Background: Programmed death-1 (PD-1)-targeted therapies that treat non-small cell lung cancer (NSCLC) to salvage exhausted CD8 T cells depends on CD28 costimulatory pathway. However, the prognostic values of CD8+CD28+ T and CD8+CD28- T in… read more here.
Keywords: cd8 cells; cd28; cell; advanced nsclc ... See more keywords
Peripheral CD8+CD28+ T lymphocytes predict the efficacy and safety of PD-1/PD-L1 inhibitors in cancer patients
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1125876
Abstract: Background Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors works by reactivating immune cells. Considering the accessibility of noninvasive liquid biopsies, it is advisable to employ peripheral blood lymphocyte subsets to predict immunotherapy outcomes.… read more here.
Keywords: cd28; cd8 cd28; cd28 cell; cd28 cells ... See more keywords