Expansion of CD4+CD8+ Double-positive T cells in Rheumatoid Arthritis Patients is Associated with Erosive Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab551
Abstract: OBJECTIVES CD4+CD8+ double-positive (DP) T cells are expanded in the peripheral blood of a subset of patients with rheumatoid arthritis (RA). This study examines the clinical significance of DP T cells in RA. METHODS In… read more here.
Keywords: cd4 cd8; double positive; cd8 double; expansion ... See more keywords
Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf0567
Abstract: An important paradigm in allogeneic hematopoietic cell transplantations (allo-HCTs) is the prevention of graft-vs-host disease (GVHD) while preserving the graft-vs-leukemia (GVL) activity of donor T cells. From an observational clinical study of adult allo-HCT recipients,… read more here.
Keywords: cd4 cd8; double positive; gvhd; pathology ... See more keywords
Distinct CD4−CD8− (Double-Negative) Memory T-Cell Subpopulations Are Associated With Indeterminate and Cardiac Clinical Forms of Chagas Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.761795
Abstract: CD4−CD8− (double-negative, DN) T cells are critical orchestrators of the cytokine network associated with the pathogenic inflammatory response in one of the deadliest cardiomyopathies known, Chagas heart disease, which is caused by Trypanosoma cruzi infection.… read more here.
Keywords: memory cells; memory; cd4 cd8; effector memory ... See more keywords
CD4/CD8 double-negative mycosis fungoides with large cell transformation and involvement of the lungs and leptomeninges.
Sign Up to like & getrecommendations! Published in 2022 at "Dermatology online journal"
DOI: 10.5070/d328257394
Abstract: Mycosis fungoides (MF), the most common cutaneous T-cell lymphoma, classically has an indolent clinical course, with lesions slowly progressing from patch to plaque to tumor stage. In some cases, the late stages of disease involve… read more here.
Keywords: cd4 cd8; cell; cd8 double; mycosis fungoides ... See more keywords