Clinical significance of CD8-positive lymphocytes on tumor cell clusters of ascites cell block in ovarian high-grade serous carcinoma.
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DOI: 10.1002/cam4.4592
Abstract: BACKGROUND The clinical significance of CD8-positive (CD8+ ) lymphocytes on tumor cell clusters of ascites cell blocks in patients with ovarian high-grade serous carcinoma (HGSC) was investigated. METHODS Among HGSC patients who underwent surgery from… read more here.
Keywords: group; cd8; cd8 lymphocytes; cell ... See more keywords
Interleukin 2 Promotes Hepatic Regulatory T Cell Responses and Protects From Biliary Fibrosis in Murine Sclerosing Cholangitis
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DOI: 10.1002/hep.30061
Abstract: In the multidrug resistance protein 2 (Mdr2)‐/‐ mouse model, low phospholipid bile instigates biliary epithelial injury, sterile inflammation, and fibrosis, thereby recapitulating disease mechanisms implicated in biliary atresia (BA) and primary sclerosing cholangitis. We hypothesize… read more here.
Keywords: fibrosis murine; cd8 lymphocytes; cd8; fibrosis ... See more keywords
Dihydroartemisinin regulates the immune system by promotion of CD8+ T lymphocytes and suppression of B cell responses
Sign Up to like & getrecommendations! Published in 2019 at "Science China Life Sciences"
DOI: 10.1007/s11427-019-9550-4
Abstract: Artemisia annua is an anti-fever herbal medicine first described in traditional Chinese medicine 1,000 years ago. Artemisinin, the extract of A. annua, and its derivatives (dihydroartemisinin (DHA), artemether, and artesunate) have been used for the… read more here.
Keywords: medicine; cd8 lymphocytes; dihydroartemisinin regulates; immune system ... See more keywords
Correlation and clinical significance of LC3, CD68+ microglia, CD4+ T lymphocytes, and CD8+ T lymphocytes in gliomas
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2018.02.044
Abstract: OBJECTIVE To investigate the relationship between the expression of microtubule-associated protein LC3 and the numbers of CD68 + microglia, CD4 + T lymphocytes and CD8 + T lymphocytes, as well as the clinical significance of those factors in gliomas. PATIENTS AND… read more here.
Keywords: cd8 lymphocytes; cd4 lymphocytes; microglia cd4; cd68 microglia ... See more keywords
p722 ferrocifen loaded lipid nanocapsules improve survival of murine xenografted-melanoma via a potentiation of apoptosis and an activation of CD8+ T lymphocytes.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120111
Abstract: Metastatic melanoma is a malignant tumor with a poor prognosis. Recent new therapeutics improved the survival of patients at a metastatic stage. However, the low response rate to immunotherapy, explained in part by resistance to… read more here.
Keywords: melanoma; cd8 lymphocytes; apoptosis; lipid nanocapsules ... See more keywords
CD8+ lymphocytes in immunity against tuberculosis.
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DOI: 10.1093/jimmun/vkaf268
Abstract: Tuberculosis (TB) is a major global health threat. Deep knowledge of the immune responses against Mycobacterium tuberculosis (Mtb) is crucial for developing effective interventions. Data support that both innate and adaptive CD8+ lymphocytes contribute to… read more here.
Keywords: cd8 lymphocytes; cd8; cd8 lymphocyte; lymphocytes immunity ... See more keywords
CXCR5+IFN-γ+CD8+ T Lymphocytes as a Potential Inhibitor of DSA Formation in Renal Transplant Recipients.
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DOI: 10.1097/tp.0000000000003152
Abstract: T recipients, especially those with underdosed immunosuppressive therapy, are at risk of posttransplant antibody development against HLA antigens of the organ donor. The de novo donor-specific antibodies (DSA) can be harmful to the transplant recipient… read more here.
Keywords: cd8 lymphocytes; transplant recipients; dsa positive; dsa ... See more keywords
Effect of Lymphocyte Subsets on Bone Density in Senile Osteoporosis: A Retrospective Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/3337622
Abstract: Background Several studies have shown that lymphocyte subsets can mediate the occurrence of osteoporosis (OP); however, the predictive ability of lymphocyte subsets in senile OP has not been elucidated. Purpose To investigate the ability of… read more here.
Keywords: density; senile osteoporosis; lymphocyte subsets; osteoporosis ... See more keywords
Abstract 3761: Regulation of metastasis by CD8 T lymphocytes
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DOI: 10.1158/1538-7445.am2019-3761
Abstract: Metastatic breast cancer is the most dreadful malignant disease that accounts for the majority of cancer-related deaths worldwide among women. A number of studies have shown that the tumor microenvironment (TME) plays a crucial role… read more here.
Keywords: cd8 lymphocytes; metastasis; cancer; regulation metastasis ... See more keywords
Abstract 4372450: Lack of CD8+ lymphocytes protects TAC mice from cerebral hypoperfusion and cognitive impairment, independently from their impact on cerebral vascular myogenic tone
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4372450
Abstract: Introduction: Arterial hypertension alters the central nervous system's structural and functional integrity, leading to the decline of cognitive functions. Experimentally, the murine model of cerebral hypertension induced by aortic coarctation (TAC) allows us to investigate… read more here.
Keywords: mice; cd8 lymphocytes; cd8 cells; myogenic tone ... See more keywords
Infiltration of CD3+ and CD8+ lymphocytes in association with inflammation and survival in pancreatic cancer
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DOI: 10.1371/journal.pone.0297325
Abstract: Background Pancreatic ductal adenocarcinomas (PDAC) have heterogeneous tumor microenvironments relatively devoid of infiltrating immune cells. We aimed to quantitatively assess infiltrating CD3+ and CD8+ lymphocytes in a treatment-naïve patient cohort and assess associations with overall… read more here.
Keywords: cd8 lymphocytes; cd3 cd8; cd8; infiltration ... See more keywords