Low DNA damage in peripheral lymphocytes of healthy elderly individuals with inverted CD4:CD8 ratio.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.060
Abstract: The aim of this study was to evaluate the DNA damage in peripheral lymphocytes and the frequencies of CD8+ T cells expressing CD25, CD28 and CD45ro in aged individuals with inverted CD4:CD8 ratio. Blood samples… read more here.
Keywords: dna damage; inverted cd4; cd8 ratio; cd4 cd8 ... See more keywords
CD4/CD8 ratio and CD4 nadir predict mortality following non-communicable disease diagnosis in adults living with HIV.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2019.0064
Abstract: OBJECTIVE Incidence of non-communicable diseases (NCDs) including cardiovascular disease (CVD), cirrhosis, and non-AIDS-defining cancers (NADCs) have been associated with HIV viremia, CD4 cell counts and CD4/CD8 ratio in persons living with HIV. This study examined… read more here.
Keywords: cd4 nadir; cd8 ratio; hiv; cd4 ... See more keywords
A lower CD4+/CD8+ ratio predicts activities of daily living decline among older adults with HIV.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0080
Abstract: BACKGROUND aging of people with human immunodeficiency virus (HIV) is a worldwide reality, and age-related conditions, including disability, have also increased. Efforts are being made to search for more specific markers of immune system malfunction,… read more here.
Keywords: cd4 cd8; cd8 ratio; decline;
Different impact of raltegravir versus efavirenz on CD4/CD8 ratio recovery in HIV-infected patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw375
Abstract: Objectives A low CD4/CD8 ratio during treated HIV identifies individuals with heightened immunoactivation and excess mortality. Whether ART regimens elicit distinct CD4/CD8 ratio recovery remains unknown. We aimed to compare the efficacy of an integrase… read more here.
Keywords: cd4 cd8; cd8 ratio; versus; normalization ... See more keywords
Long-term trends in CD4 cell counts, CD8 cell counts, and the CD4: CD8 ratio: ART Cohort Collaboration (ART-CC) Study.
Sign Up to like & getrecommendations! Published in 2018 at "AIDS"
DOI: 10.1097/qad.0000000000001848
Abstract: OBJECTIVE Model trajectories of CD4 and CD8 cell counts after starting combination antiretroviral therapy (ART), and use the model to predict trends in these counts and the CD4:CD8 ratio. DESIGN Cohort study of antiretroviral-naïve HIV-positive… read more here.
Keywords: cd8 ratio; count; cd4 cd8; cell counts ... See more keywords
The cerebrospinal fluid CD4/CD8 ratio and interleukin‐6 and ‐10 levels in neurosarcoidosis: a multicenter, pragmatic, comparative study
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13975
Abstract: Neurosarcoidosis is a rare inflammatory disorder of unknown cause. The aim of this study was to evaluate the value of T/B lymphocyte population counts and the concentrations of the cytokines interleukin (IL) 6 and IL‐10… read more here.
Keywords: cd4 cd8; cd8 ratio; study; fluid cd4 ... See more keywords
Correlation between CD4/CD8 ratio and neurocognitive performance during early HIV infection
Sign Up to like & getrecommendations! Published in 2022 at "HIV Medicine"
DOI: 10.1111/hiv.13411
Abstract: CD4/CD8 ratio is a marker of immune activation in HIV infection and has been associated with neurocognitive performance during chronic infection, but little is known about the early phases. read more here.
Keywords: cd4 cd8; neurocognitive performance; infection; cd8 ratio ... See more keywords
Combining CD4 recovery and CD4: CD8 ratio restoration as an indicator for evaluating the outcome of continued antiretroviral therapy: an observational cohort study
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open"
DOI: 10.1136/bmjopen-2017-016886
Abstract: Objectives Immune recovery following highly active antiretroviral therapy (HAART) is commonly assessed by the degree of CD4 reconstitution alone. In this study, we aimed to assess immune recovery by incorporating both CD4 count and CD4:CD8… read more here.
Keywords: recovery; cd8; cd4 cd8; cd8 ratio ... See more keywords
CD4+/CD8+ ratio positively correlates with coronary plaque instability in unstable angina pectoris patients but fails to predict major adverse cardiovascular events
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/2040622320922020
Abstract: Background: The association between CD4+/CD8+ ratio and coronary plaque instability in patients with unstable angina pectoris (UAP) has not been investigated. We sought to elucidate the correlation between CD4+/CD8+ ratio and plaque instability in this… read more here.
Keywords: cd8 ratio; plaque instability; cd4 cd8;
CD4/CD8 ratio normalization rates and low ratio as prognostic marker for non-AIDS defining events among long-term virologically suppressed people living with HIV
Sign Up to like & getrecommendations! Published in 2018 at "AIDS Research and Therapy"
DOI: 10.1186/s12981-018-0200-4
Abstract: BackgroundImmune restoration is often incomplete after ART in HIV patients, both quantitatively and qualitatively. We studied the incidence and probability of CD4/CD8 normalization in an adult Thai HIV cohort and explored the predictive value of… read more here.
Keywords: normalization; cd8 ratio; cd4 cd8; ratio ... See more keywords
Role of CD4/CD8 ratio on the incidence of tuberculosis in HIV-infected patients on antiretroviral therapy followed up for more than a decade
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0233049
Abstract: Background The role of CD4/CD8 ratio on the incidence of tuberculosis (TB) in patients on antiretroviral therapy (ART) is unknown. Thus, we sought to determine whether the CD4/CD8 ratio was associated with development of TB… read more here.
Keywords: cd8 ratio; cd4; cd4 cd8; art ... See more keywords