CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202048614
Abstract: Regulatory T cells (Tregs) play a key role in the peripheral self‐tolerance and preventing autoimmunity. While classical CD4+ Foxp3+ Tregs are well established, their CD8+ counterparts are still controversial in many aspects including their phenotypic… read more here.
Keywords: cd8; cd8 tregs; cells cd8; revisited heterogeneous ... See more keywords
Helios Expression Is Downregulated on CD8+ Treg in Two Mouse Models of Lupus During Disease Progression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.922958
Abstract: T-cell–mediated autoimmunity reflects an imbalance in this compartment that is not restored by tolerogenic immune cells, e.g., regulatory T cells or tolerogenic dendritic cells (tolDCs). Although studies into T-cell equilibrium have mainly focused on regulatory… read more here.
Keywords: cd8 tregs; expression downregulated; mouse; downregulated cd8 ... See more keywords
Reduced Expression of PD-1 in Circulating CD4+ and CD8+ Tregs Is an Early Feature of RRMS
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23063185
Abstract: Altered regulatory T cell (Treg) function could contribute to MS. The expression of activating and inhibitory receptors influences the activity of Tregs. Our aim was to investigate T cell phenotypes in relapsing–remitting MS (RRMS) patients… read more here.
Keywords: cd4 cd8; cell; cd8 tregs; feature rrms ... See more keywords