Transcriptome of CD8+ tumor-infiltrating T cells: a link between diabetes and colorectal cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02879-7
Abstract: There is an increased risk of colorectal cancer (CRC) development in patients with non-insulin-dependent type 2 diabetes. CD8+ T cells have been implicated in diabetes and are crucial for anti-tumor immunity. However, transcriptomic profiling for… read more here.
Keywords: cd8 tumor; colorectal cancer; tumor infiltrating; cancer ... See more keywords
CT-based radiomics signature to predict CD8+ tumor infiltrating lymphocytes in non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Acta Radiologica"
DOI: 10.1177/02841851221126596
Abstract: Background An abundance of CD8+ tumor infiltrating lymphocytes (TILs) in the center of solid tumors is a reliable predictive biomarker for patients eligible for immunotherapy. Purpose To develop a computed tomography (CT)-based radiomics signature for… read more here.
Keywords: tumor infiltrating; abundance cd8; based radiomics; cd8 tumor ... See more keywords
Association of high CD8+ tumor infiltrating lymphocytes at prostatectomy with improved survival of prostate cancer patients.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.5068
Abstract: 5068Background: High CD8+ tumor infiltrating lymphocytes (TILs) are associated with improved survival in many solid tumors. However, its prognostic value in prostate cancer (PCa) is unclear. Method... read more here.
Keywords: cd8 tumor; improved survival; infiltrating lymphocytes; prostate cancer ... See more keywords
Chemoradiation-induced alteration of programmed death-ligand 1 and CD8+ tumor-infiltrating lymphocytes in rectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.570
Abstract: 570 Background: DNA damage and subsequent neoantigen formation has been hypothesized as a mechanismfor radiotherapy and PD-1/PD-L1 pathway inhibition to synergize in an antitumor immune response. We investigated neoadjuvant chemoradiotherapy (nCRT)-induced changes in CD8+ tumor… read more here.
Keywords: expression; rectal cancer; cd8 tumor; tumor ... See more keywords
Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.680973
Abstract: The immune infiltrate within tumors has proved to be very powerful in the prognostic stratification of patients and much attention is also being paid towards its predictive value. In this work we therefore aimed at… read more here.
Keywords: impact expression; cd8 tumor; cd8; expression prognostic ... See more keywords