CD80/CD86 signaling contributes to the proinflammatory response of Staphylococcus aureus in the airway
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.01.016
Abstract: HighlightsCD80/CD86 signaling contributes to mortality due to S. aureus pneumonia.Absence of CD80/Cd86 leads to improved levels of alveolar macrophages.CD80/CD86 signaling significantly contributes to inflammatory cytokine production. &NA; It was posited that the initial host response… read more here.
Keywords: response; cd86; cd80 cd86; signaling contributes ... See more keywords
Identification of another primordial CD80/86 molecule in rainbow trout: Insights into the origin and evolution of CD80 and CD86 in vertebrates
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.08.007
Abstract: Abstract In mammals, the binding of distinct costimulatory ligands CD80 and CD86 to their receptors is essential for optimal T cell activation. Previous studies have shown that only a single CD80/86 gene exists in rainbow… read more here.
Keywords: cd80 cd86; rainbow trout; cd80; cd80 genes ... See more keywords
Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-2867
Abstract: Localized expression of effector molecules can initiate antitumor responses through engagement of specific receptors on target cells in the tumor microenvironment. These locally induced responses may also have a systemic effect, clearing additional tumors throughout… read more here.
Keywords: cd80 cd86; ox40l cd80; mrna; antitumor ... See more keywords
Modulation of Regulatory T Cells Activity by Distinct CD80 and CD86 Interactions With CD28/CTLA-4 in Chagas Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.750876
Abstract: Chagas cardiomyopathy is the symptomatic cardiac clinical form (CARD) of the chronic phase of Chagas disease caused by Trypanosoma cruzi infection. It was described as the most fibrosing cardiomyopathies, affecting approximately 30% of patients during… read more here.
Keywords: cd80 cd86; treg; cd80; chagas cardiomyopathy ... See more keywords
The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.726448
Abstract: Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive,… read more here.
Keywords: immune checkpoint; aggressive pituitary; adenomas; pituitary adenomas ... See more keywords