Abstract 4550: CD80 vIgD-Fc proteins combine checkpoint antagonism and costimulatory signaling for potent antitumor immunity
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DOI: 10.1158/1538-7445.am2018-4550
Abstract: Introduction: PD-1 pathway antagonists have revealed the importance of checkpoint pathways in regulating antitumor immunity, but an existing immune response is generally required for clinical efficacy. Specific T cell costimulation through CD28 is central to… read more here.
Keywords: cd80 vigd; antitumor immunity; vigd proteins; cd80 ... See more keywords