Differential regulation of CD8+CD86+ Vγ1.1+ γδT cell responses in skin barrier tissue protection and homeostatic maintenance
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202249793
Abstract: Compared to αβT cells, γδT cells are more innate‐like and preferentially function as the first line of defense in barrier tissues. Certain populations of γδT cells possess adaptive immune cell properties but their regulation is… read more here.
Keywords: cd8 cd86; cell; skin cells; cd86 ... See more keywords
CD80/CD86 signaling contributes to the proinflammatory response of Staphylococcus aureus in the airway
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.01.016
Abstract: HighlightsCD80/CD86 signaling contributes to mortality due to S. aureus pneumonia.Absence of CD80/Cd86 leads to improved levels of alveolar macrophages.CD80/CD86 signaling significantly contributes to inflammatory cytokine production. &NA; It was posited that the initial host response… read more here.
Keywords: response; cd86; cd80 cd86; signaling contributes ... See more keywords
Polymorphisms of RPS6KB1 and CD86 associates with susceptibility to multiple sclerosis in Iranian population
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Research"
DOI: 10.1080/01616412.2016.1278108
Abstract: Abstract Objective: Multiple sclerosis (MS) is the most prevalent disorder of nervous system inflammation which involves demyelination of spinal cord; this process depends on both environmental and genetic susceptibility factors. In the present study, we… read more here.
Keywords: iranian population; genotype; cd86; multiple sclerosis ... See more keywords
Abstract LB160: PD-L1-expressing B cells promote murine breast cancer development and mediate the response to anti-PD-L1 immune checkpoint inhibitor to upregulate B-cell CD86 and inhibit tumor growth
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1158/1538-7445.am2021-lb160
Abstract: B cells promote tumor development in murine models of breast cancer (BCa), including - as we have shown - by producing pleiotropic cytokine IL-27, which upregulates expression of the PD-L1 immune checkpoint in BCa cells… read more here.
Keywords: response; development; cancer; cell ... See more keywords
A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood donors independent of age and sex
Sign Up to like & getrecommendations! Published in 2020 at "BMC Immunology"
DOI: 10.1186/s12865-020-00343-2
Abstract: Background The use of anti-B cell based therapies in immune-mediated diseases targeting general B cell markers or molecules important for B cell function has increased the clinical needs of monitoring B cell subpopulations. Results We… read more here.
Keywords: btla; cell subtypes; cd86; expression ... See more keywords
Talaromyces marneffei Can Capture CD86 Proteins of Macrophages in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s389612
Abstract: Background Talaromyces marneffei (T. marneffei) is a thermally dimorphic fungus endemic to Southeast Asia that causes human systemic infection. Our earlier immunohistochemical studies revealed that the organisms were markedly labeled with the CD86 antigen in… read more here.
Keywords: cd86 proteins; microscopy; cd86; capture cd86 ... See more keywords