Single-cell transcriptomics of human gut T cells identifies cytotoxic CD4+CD8A+ T cells related to mouse CD4 cytotoxic T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.977117
Abstract: Cytotoxic CD4+ T cells (CD4-CTLs) show the presence of cytolytic granules, which include the enzymes granzyme and perforin. The cells have a pathogenic and protective role in various diseases, including cancer, viral infection, and autoimmune… read more here.
Keywords: cell; cytotoxic cd4; cd4 cells; cd4 ... See more keywords
CD8A as a Prognostic and Immunotherapy Predictive Biomarker Can Be Evaluated by MRI Radiomics Features in Bladder Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14194866
Abstract: Simple Summary It is necessary to explore a reliable predictive biomarker for immunotherapeutic strategies in bladder cancer. As an important member of tumor-infiltrating immune cells, cytotoxic T cells are the ultimate effectors of cancer rejection… read more here.
Keywords: cd8a; predictive biomarker; expression; bladder cancer ... See more keywords
CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models
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DOI: 10.7150/thno.37513
Abstract: Predicting the outcome of immunotherapy is essential for efficient treatment. The recent clinical success of immunotherapy is increasingly changing the paradigm of cancer treatment. Accordingly, the development of immune-based agents is accelerating and the number… read more here.
Keywords: dfo; 89zr dfo; response; cd8a ... See more keywords