Boyden Chamber Assay to Study of Cell Migration Induced by Metalloprotease Cleaved-CD95L.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6780-3_12
Abstract: CD95 receptor, also called Fas or Apo-1, is a member of the tumor necrosis factor receptors (TNF-R) superfamily (Itoh and Nagata, J Biol Chem 268:10932-10937, 1993). Its cognate ligand, CD95L, is a transmembrane cytokine, which… read more here.
Keywords: boyden chamber; metalloprotease cleaved; cleaved cd95l; cell ... See more keywords
P13.17 CD95 gene silencing affects growth and invasiveness of glioma-initiating cells in a CD95L-independent manner
Sign Up to like & getrecommendations! Published in 2021 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noab180.124
Abstract: CD95 (Fas/APO-1) holds a dual role of potential relevance in tumor development. CD95-CD95 ligand (CD95L) signaling regulates apoptotic cell death in CD95-expressing cells, but non-apoptotic, tumor-promoting CD95-CD95L signaling has been likewise described. Therapeutic stimulation of… read more here.
Keywords: cd95 cd95l; tumor promoting; cd95l; gic ... See more keywords
CD95L and Anti-Tumor Immune Response: Current Understanding and New Evidence
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Management and Research"
DOI: 10.2147/cmar.s297499
Abstract: Abstract The ability of FasL/CD95L to induce apoptosis in various Fas/CD95-expressing cells has been described in the context of hematopoiesis or thymic elimination of self-reactive T cells and resolution of an acute immune response under… read more here.
Keywords: immune response; cd95l; anti tumor; cancer ... See more keywords
The dual role of the CD95 and CD95L signaling pathway in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1029737
Abstract: Binding of CD95, a cell surface death receptor, to its homologous ligand CD95L, transduces a cascade of downstream signals leading to apoptosis crucial for immune homeostasis and immune surveillance. Although CD95 and CD95L binding classically… read more here.
Keywords: cd95l; cd95 cd95l; role cd95; tumor ... See more keywords
Role of metalloproteases in the CD95 signaling pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1074099
Abstract: CD95L (also known as FasL or CD178) is a member of the tumor necrosis family (TNF) superfamily. Although this transmembrane ligand has been mainly considered as a potent apoptotic inducer in CD95 (Fas)-expressing cells, more… read more here.
Keywords: metalloproteases cd95; role; cd95 signaling; cd95l ... See more keywords