Anti-human CD99 antibody exerts potent antitumor effects in mantle cell lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02789-0
Abstract: CD99 is a surface molecule expressed on various cell types including cancer cells. Expression of CD99 on multiple myeloma is associated with CCND1-IGH fusion/t(11;14). This translocation has been reported to be a genetic hallmark of… read more here.
Keywords: antibody; mantle cell; cell; cd99 ... See more keywords
CD99 mediates neutrophil transmigration through the bEnd.3 monolayer via the induction of oxygen-glucose deprivation.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.159
Abstract: AIM/BACKGROUND CD99 participate in neutrophil infiltration after inflammatory events; however, despite the important role of inflammation in ischemic stroke, the role of CD99 in ischemic stroke remains unclear. METHOD In the present study, we detected… read more here.
Keywords: transmigration; cd99 mediates; glucose deprivation; oxygen glucose ... See more keywords
Abstract 2875: Targeted therapy of Ewing’s sarcoma by human anti CD99 targeted hybrid polymerized liposomal nanoparticles (HPLNs) encapsulating anticancer agents
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-2875
Abstract: Most anticancer therapies are unspecific and therefore inevitably lead to off-target toxicity. To overcome these shortcomings, targetable hybrid polymerization liposomal nanoparticles (HPLNs) have been invented. Multiple innovative and proprietary technologies have been developed to enable… read more here.
Keywords: liposomal nanoparticles; hplns encapsulating; tumor; cd99 ... See more keywords
Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2016-08-733394
Abstract: CD99 is a crucial regulator of the transmigration (diapedesis) of leukocytes through the blood vessel wall. Here, we report that CD99 acts at 2 different steps in the extravasation process. In agreement with previous antibody-blocking… read more here.
Keywords: cd99 supports; arrest; endothelial cells; endothelial cd99 ... See more keywords
The presence of membrane bound CD99 ligands on leukocyte surface
Sign Up to like & getrecommendations! Published in 2020 at "BMC Research Notes"
DOI: 10.1186/s13104-020-05347-0
Abstract: Objective CD99, a leukocyte surface molecule, reportedly plays an important role in several cellular processes. However, the role of CD99 in T cell regulation remains unclear, as the CD99 ligand associated with T-cell regulation has… read more here.
Keywords: cd99 ligands; bound cd99; cd99 ligand; cell ... See more keywords
Interaction of CD99 and its ligand upregulates IL-6 and TNF-α upon T cell activation
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0217393
Abstract: CD99 has been reported to be involved in T cell regulation. CD99 ligand involvement in the regulation of T cell activation has been postulated. In this study, recombinant CD99 proteins were produced and used as… read more here.
Keywords: cd99 ligand; cell activation; interaction; cell ... See more keywords
Cell adhesion molecule CD99 in cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524023666221007143513
Abstract: The CD99 antigen is a transmembrane protein expressed in a broad variety of tissues, particularly in hematopoietic cells, thymus, endothelial cells, etc. It participates in several crucial biological processes including cell adhesion, migration, death, differentiation… read more here.
Keywords: cell; cd99; cd99 cancer; cancer ... See more keywords
Canine Mammary Neoplasia Induces Variations in the Peripheral Blood Levels of CD20, CD45RA, and CD99
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119222
Abstract: The idea of using tumour biomarkers as diagnostic tools is progressively increasing. Of these, serum biomarkers are of particular interest, as they can provide rapid results. In the present study, serum samples from 26 bitches… read more here.
Keywords: cd20 cd45ra; cd99; serum samples; mammary neoplasia ... See more keywords