Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces
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DOI: 10.1007/s11427-019-1559-y
Abstract: CRISPR/Cas-mediated genome editing has greatly facilitated the study of gene function in Streptomyces. However, it could not be efficiently employed in streptomycetes with low homologous recombination (HR) ability. Here, a deaminase-assisted base editor dCas9-CDA-ULstr was… read more here.
Keywords: genome editing; cda ulstr; base; dcas9 cda ... See more keywords