CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes.
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DOI: 10.1242/jcs.252924
Abstract: Mammalian oocytes are arrested at meiotic prophase I. The dual-specificity phosphatase CDC25B is essential for cyclin-dependent kinase 1 (CDK1) activation that drives resumption of meiosis. CDC25B reverses the inhibitory effect of the protein kinases WEE1/MYT1… read more here.
Keywords: metaphase; cdc25b oocytes; cdk1 activation; cdc25b ... See more keywords