Articles with "cdc25c" as a keyword



CDC25c expression in patients with myelofibrosis is associated with stronger myeloproliferation and shorter overall survival

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Published in 2020 at "Wiener klinische Wochenschrift"

DOI: 10.1007/s00508-020-01738-2

Abstract: Cell division cycle 25c (CDC25c) is a gene coding a phosphatase controlling entry into mitosis upon activation through Polo-like kinase 1 (PLK1) and serves as a key regulator of cell division. The CDC25c was reported… read more here.

Keywords: cdc25c; cdc25c expression; myelofibrosis; expression ... See more keywords

Overexpression of CDC25C affects the cell cycle of ovarian granulosa cells from adult and young goats

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Published in 2018 at "Electronic Journal of Biotechnology"

DOI: 10.1016/j.ejbt.2017.10.008

Abstract: Background: CDC25 is a dual-specificity phosphatase that was first identified in the yeast Schizosaccharomyces pombe as a cell cycle-defective mutant. Although CDC25 is involved in the cell cycle of ovarian granulosa cells, the CDC25 signaling… read more here.

Keywords: ovarian granulosa; granulosa cells; granulosa; cdc25c ... See more keywords

CDC25C is a prognostic biomarker and correlated with mitochondrial homeostasis in pancreatic adenocarcinoma

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2078940

Abstract: ABSTRACT Pancreatic adenocarcinoma (PAAD) is a common digestive tract malignant tumor with an extremely poor prognosis. The survival and prognosis may significantly improve if it is diagnosed early. Therefore, identifying biomarkers for early diagnosis is… read more here.

Keywords: mitochondrial homeostasis; cdc25c; pancreatic adenocarcinoma; paad ... See more keywords

AURKA/PLK1/CDC25C Axis as a Novel Therapeutic Target in INI1‐Deficient Epithelioid Sarcoma

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Published in 2025 at "Cancer Science"

DOI: 10.1111/cas.16438

Abstract: Effective therapeutic strategies for epithelioid sarcoma (EpS), a high‐grade soft tissue sarcoma characterized by loss of integrase interactor 1 (INI1), have not yet been developed. The present study therefore investigated the association between INI1 loss… read more here.

Keywords: aurka plk1; plk1 cdc25c; cdc25c axis; cdc25c ... See more keywords

Downregulation of CDC25C in NPCs Disturbed Cortical Neurogenesis

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021505

Abstract: Cell division regulators play a vital role in neural progenitor cell (NPC) proliferation and differentiation. Cell division cycle 25C (CDC25C) is a member of the CDC25 family of phosphatases which positively regulate cell division by… read more here.

Keywords: cell; role; cdc25c npcs; cortical neurogenesis ... See more keywords

Cell division cyclin 25C knockdown inhibits hepatocellular carcinoma development by inducing endoplasmic reticulum stress

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Published in 2024 at "World Journal of Gastroenterology"

DOI: 10.3748/wjg.v30.i19.2564

Abstract: BACKGROUND Cell division cyclin 25C (CDC25C) is a protein that plays a critical role in the cell cycle, specifically in the transition from the G2 phase to the M phase. Recent research has shown that… read more here.

Keywords: cdc25c; hcc; stress; cell ... See more keywords