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   Articles with "cdc2s" as a keyword



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Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination.

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recommendations! Published in 2020 at "Cell reports"

DOI: 10.1016/j.celrep.2019.12.096

Abstract: Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are currently under evaluation for use in cancer vaccines. Although both DC subsets can activate adaptive and innate lymphocytes, their capacity to recruit such… read more here.

Keywords: human pdcs; melanoma patients; vaccination; cdc2s ... See more keywords
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Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection

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recommendations! Published in 2020 at "Immunity"

DOI: 10.1016/j.immuni.2020.04.005

Abstract: Summary The phenotypic and functional dichotomy between IRF8+ type 1 and IRF4+ type 2 conventional dendritic cells (cDC1s and cDC2s, respectively) is well accepted; it is unknown how robust this dichotomy is under inflammatory conditions,… read more here.

Keywords: inf cdc2s; immunity; infection; type ... See more keywords
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Notch2-dependent DC2s mediate splenic germinal center responses

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recommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1809925115

Abstract: Significance High-affinity antibody responses involve selection of B cells in the germinal center (GC) by cognate interactions with T follicular helper (TFH) cells, which in turn must first be activated by classical dendritic cells (cDCs).… read more here.

Keywords: germinal center; notch2 dependent; tfh; cell ... See more keywords
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AB0176 MITOGEN- AND STRESS-ACTIVATED PROTEIN KINASE-1 (MSK1) AS THE LINK BETWEEN MIR-130A-DYSREGULATION AND CDC2-ACTIVATION IN SJöGREN’S SYNDROME

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recommendations! Published in 2019 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2019-eular.6806

Abstract: Background: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands and dryness of mouth and eyes. T and B lymphocytes that infiltrate the salivary glands play a… read more here.

Keywords: production; msk1; pss; activation ... See more keywords

CD109 Pumps Up Type Two Dendritic Cells for Allergic Responses in the Airways

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recommendations! Published in 2022 at "American Journal of Respiratory Cell and Molecular Biology"

DOI: 10.1165/rcmb.2022-0405ed

Abstract: Allergic airway inflammation is driven largely by Th2 (type 2 T helper) cells. Although these cells were first identified more than 3 decades ago (1), much remains to be learned of the molecular mechanisms that… read more here.

Keywords: cell; cdc2s; dcs; lung ... See more keywords