LAUSR

CDC42 binds PAK4 via an extended GTPase-effector interface

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1 Published in 2017 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.2210/pdb5upk/pdb

Abstract: The p21-activated kinase (PAK) group of serine/threonine kinases are downstream effectors of RHO GTPases and play important roles in regulation of the actin cytoskeleton, cell growth, survival, polarity, and development. Here we probe the interaction… read more here.

Keywords: cdc42; kinase; binds pak4; pak4 via ... See more keywords