miR-185-5p Regulates Inflammation and Phagocytosis through CDC42/JNK Pathway in Macrophages
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DOI: 10.3390/genes13030468
Abstract: Macrophage activation is an essential component of systemic chronic inflammation and chronic inflammatory diseases. Emerging evidence implicates miR-185-5p in chronic inflammation diseases. However, the regulatory role of miR-185-5p in macrophage pro-inflammatory activation has not been… read more here.
Keywords: cdc42 jnk; cdc42; pro inflammatory; mir 185 ... See more keywords
Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis
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DOI: 10.3390/ijms232416137
Abstract: Background: Thrombocytopenia has long been considered an important complication of chemotherapy and radiotherapy, which severely limits the effectiveness of cancer treatment and the overall survival of patients. However, clinical treatment options are extremely limited so… read more here.
Keywords: ruxolitinib; jnk pathway; rac1 cdc42; cdc42 jnk ... See more keywords