Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi
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DOI: 10.1080/21505594.2019.1620063
Abstract: ABSTRACT Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and geranylgeranyltransferase type-I (GGTase-I), each composed of a shared α-subunit and a unique β-subunit. GGTase-I enzymes are validated drug… read more here.
Keywords: protein geranylgeranylation; virulence; cell wall; subunit ... See more keywords