Structural insights into Cdc45 function: was there a nuclease at the heart of the ancestral replisome?
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DOI: 10.1016/j.bpc.2016.11.011
Abstract: The role of Cdc45 in genomic duplication has remained unclear since its initial identification as an essential replication factor. Recent structural studies of Cdc45 and the evolutionarily-related archaeal GAN and bacterial RecJ nucleases have provided… read more here.
Keywords: function nuclease; cdc45; structural insights; cdc45 function ... See more keywords