Functions and regulation of the Polo-like kinase Cdc5 in the absence and presence of DNA damage
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DOI: 10.1007/s00294-017-0727-2
Abstract: Polo-like kinases are essential cell cycle regulators that are conserved from yeast to humans. Unlike higher eukaryotes, who express multiple Polo-like kinase family members that perform many important functions, budding yeast express only a single… read more here.
Keywords: dna damage; like kinase; cdc5; polo like ... See more keywords
Saccharomyces cerevisiae polo-like kinase, Cdc5 exhibits ATP-dependent Mg2+-enhanced kinase activity in vitro
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DOI: 10.1016/j.heliyon.2019.e03050
Abstract: Phosphorylation of proteins on serine/threonine residues represents an important biochemical mechanism to regulate several cellular processes. Polo-like kinases (PLKs) are a family of serine-threonine kinases that play an imminent role in cell cycle regulation in… read more here.
Keywords: cdc5; kinase; kinase activity; gst cdc5 ... See more keywords