Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Basic Research in Cardiology"
DOI: 10.1007/s00395-022-00913-y
Abstract: Cardiosphere-derived cells (CDCs) generated from human cardiac biopsies have been shown to have disease-modifying bioactivity in clinical trials. Paradoxically, CDCs’ cellular origin in the heart remains elusive. We studied the molecular identity of CDCs using… read more here.
Keywords: cells cdcs; cardiosphere derived; molecular identity; cell ... See more keywords
Characterization of encapsulated porcine Cardiosphere-Derived Cells embedded in 3D alginate matrices.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120454
Abstract: Myocardial infarction is caused by an interruption of coronary blood flow, leading to one of the main death causes worldwide. Current therapeutic approaches are palliative and not able to solve the loss of cardiac tissue.… read more here.
Keywords: alginate; characterization encapsulated; cdcs; cardiosphere derived ... See more keywords
Profiles of amino acids and biogenic amines in the plasma of Cri‐du‐Chat patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.03.034
Abstract: &NA; Cri‐du‐chat syndrome (CDCS) is a rare innate disease attributed to chromosome 5p deletion characterized by a cat‐like cry, craniofacial malformation, and altered behavior of affected children. Metabolomic analysis and a chemometric approach allow description… read more here.
Keywords: amino acids; amino acid; cdcs; cri chat ... See more keywords
Carbide-derived carbon obtained via bromination of titanium carbide: Comparative analysis with chlorination and hydrogen storage studies
Sign Up to like & getrecommendations! Published in 2019 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2018.06.037
Abstract: Abstract Carbide-derived carbons (CDCs) are synthesized from TiC micropowder via gas phase bromination at the temperature range of 350–1150 °C. The resultant carbon materials demonstrate high specific surface areas and micropore volumes of up to 1745 m2 g−1… read more here.
Keywords: hydrogen; bromination; cdcs; carbide derived ... See more keywords
Therapeutic potential of s-cdcs in myocardial infarction: interactions with standard drugs
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Surgery"
DOI: 10.1093/bjs/znae322.028
Abstract: Myocardial infarction (MI) remains a leading global cause of mortality and is commonly treated with Captopril, Spironolactone, and Bisoprolol. Emerging therapies, such as the secretome derived from cardiosphere-derived cells (S-CDCs), have shown potential in reducing… read more here.
Keywords: standard drugs; cdcs; myocardial infarction; captopril spironolactone ... See more keywords
P5387CRISPR/dCas9 Activated Expression of Cardiomyocyte Differentiation Factors in CDCs in Myocardial Infarctions
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0347
Abstract: Existing therapies against myocardial infarction (MI) involve disease management by preventing additional damage to the heart muscle. However, new treatment strategies are in greater demand, which deems to focus on restoring cardiac function by replacing… read more here.
Keywords: differentiation factors; cdcs; expression; differentiation ... See more keywords
Marginal zone B cells acquire dendritic cell functions by trogocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abf7470
Abstract: Marginal zone (MZ) B cells produce broad-spectrum antibodies that protect against infection early in life. In some instances, antibody production requires MZ B cells to display pathogen antigens bound to major histocompatibility complex class II… read more here.
Keywords: mhc; trogocytosis; cdcs; zone cells ... See more keywords
Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-004268
Abstract: Background Dendritic cells (DCs) are professional antigen presenting cells that initiate immune defense to pathogens and tumor cells. Human tumors contain only few DCs that mostly display a non-activated phenotype. Hence, activation of tumor-associated DCs… read more here.
Keywords: human tumor; tl8 506; cdcs; blood ... See more keywords
Advancing genotype-phenotype analysis through 3D facial morphometry: insights from Cri-du-Chat syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Genetics"
DOI: 10.1136/jmg-2025-110940
Abstract: Purpose Facial dysmorphism is a feature of many monogenic disorders and is important in diagnostics, variant interpretation and nosology. Nevertheless, comprehensively assessing the complex facial shape changes associated with specific syndromes remains challenging. Here, we… read more here.
Keywords: chat syndrome; genotype phenotype; facial morphometry; nosology ... See more keywords
Novel Lymphoid Pathway of Human Plasmacytoid and Conventional Dendritic Cells
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-121448
Abstract: [Introduction] Dendritic cells (DCs) play a central role in initiation and regulation of immune response. Human plasmacytoid DCs (pDCs) as well as conventional DCs (cDCs) were shown to differentiate from multi-lymphoid progenitors (MLPs) as well… read more here.
Keywords: research; cdcs; prob; research funding ... See more keywords
Comprehensive evaluation of technical support capacity for occupational disease surveillance and assessment of CDCs in Sichuan Province, China
Sign Up to like & getrecommendations! Published in 2025 at "BMC Health Services Research"
DOI: 10.1186/s12913-025-12451-z
Abstract: When the health administration department re-assumed the responsibilities for occupational safety and health supervision and management in 2018, the Chinese government allocated special funds annually to the Centers for Disease Control and Prevention (CDCs) at… read more here.
Keywords: capacity; sichuan province; cdcs; cdcs sichuan ... See more keywords