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Published in 2019 at "Gastric Cancer"
DOI: 10.1007/s10120-019-00945-9
Abstract: IntroductionThe contribution of CDH1 germline variants to gastric cancer burden among young adults is unknown in Brazil. We aimed to evaluate the frequency of CDH1 germline variants and the diet/lifestyle habits in early age onset…
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Keywords:
gastric cancer;
cdh1;
cdh1 germline;
germline variants ... See more keywords
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Published in 2020 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2020.151473
Abstract: AIMS CDH1 germline mutation is associated with high penetrance of hereditary diffuse gastric cancer (HDGC). Due to the lack of endoscopically identifiable lesions, routine surveillance is ineffective in the early detection of gastric cancer, and…
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Keywords:
germline mutation;
examination;
risk reduction;
gastrectomy ... See more keywords
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Published in 2020 at "Cancers"
DOI: 10.3390/cancers12061598
Abstract: E-cadherin (CDH1 gene) germline mutations are associated with the development of diffuse gastric cancer in the context of the so-called hereditary diffuse gastric syndrome, and with an inherited predisposition of lobular breast carcinoma. In 2019,…
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Keywords:
cdh1;
gastric breast;
multidisciplinary clinical;
cdh1 germline ... See more keywords