Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20043-7
Abstract: TP53 mutation (i.e., loss of normal-p53) may evoke epithelial-mesenchymal transition (EMT), which was previously attributed to loss of certain miRNAs. However, not all epithelial cells undergo EMT upon TP53 mutation, and the p53-miRNA axis may… read more here.
Keywords: integrity; expression; cdh1 locus; p53 binding ... See more keywords