FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.03.067
Abstract: SUMMARY Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant accumulation of collagen-secreting myofibroblasts. Development of effective therapies is limited due to incomplete understanding of molecular mechanisms regulating myofibroblast expansion. FOXF1 transcription factor is expressed in… read more here.
Keywords: foxf1 inhibits; inhibits pulmonary; fibrosis; cdh11 ... See more keywords
MiRNA-451a inhibits airway remodeling by targeting Cadherin 11 in an allergic asthma model of neonatal mice.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106440
Abstract: Airway remodeling happens in childhood asthma, in parallel with, but not necessarily subsequent to, airway inflammation. The differentiation of airway epithelial cells into myofibroblasts via epithelial-mesenchymal-transition (EMT) is one of the mechanisms underlying airway remodeling.… read more here.
Keywords: cdh11; mirna 451a; asthma model; airway remodeling ... See more keywords
Effect of Cadherin-11 on the Proliferation, Migration, and ECM Synthesis of Chondrocyte
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1155/2023/9985334
Abstract: Nonsyndromic microtia is a kind of congenital ear malformation with unclear pathogenic genes. Cadherin-11 (CDH11, OB-cadherin) is a member of the cadherin family, which has been demonstrated to play important roles in controlling morphogenesis and… read more here.
Keywords: effect; proliferation; chondrocyte; microtia ... See more keywords
Cadherin-11 Regulates Macrophage Development and Function
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.795337
Abstract: Cadherin-11 (CDH11) is a cell-cell adhesion protein that has previously been reported to play an important role in the pathogenesis of pulmonary fibrosis. It is expressed on macrophages in the fibrotic lung. However, the role… read more here.
Keywords: function; bone marrow; macrophage development; cdh11 ... See more keywords
The role of cadherin-11 in microcystin-LR-induced migration and invasion in colorectal carcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2017.7458
Abstract: The present study aimed to explore whether microcystin-LR (MC-LR; a well-known cyanobacterial toxin produced in eutrophic lakes or reservoirs) induced tumor progression by activating cadherin-11(CDH11). A previous tumor metastasis PCR array demonstrated that MC-LR exposure… read more here.
Keywords: microcystin; cdh11; migration; cadherin ... See more keywords
Clinical and prognostic association of oncogene cadherin 11 in gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.11531
Abstract: The abnormal expression of cadherin-11 (CDH11) affects the progression of several types of cancer. However, the expression pattern and prognostic value of CDH11 in gastric cancer (GC) have not been reported. In the present study,… read more here.
Keywords: gastric cancer; expression cdh11; cdh11; cancer ... See more keywords