Serine peptidase inhibitor Kazal type 1 (SPINK1) as novel downstream effector of the cadherin-17/β-catenin axis in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Oncology"
DOI: 10.1007/s13402-017-0332-x
Abstract: BackgroundHepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. Previously, we reported that cadherin-17 (CDH17) and its related CDH17/β-catenin axis may be responsible for inducing HCC in a subset of patients exhibiting… read more here.
Keywords: hcc; catenin; cdh17; expression ... See more keywords
PO-066 Knockdown of cadherin 17 inactivates WNT signalling pathway and induces apoptosis in colorectal cancer cells
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DOI: 10.1136/esmoopen-2018-eacr25.110
Abstract: Introduction Large scale sequencing studies have identified that 93% of the colorectal cancer (CRC) patients carry at least one mutation in genes implicated in Wnt signalling pathway. Notably, majority of the CRC patients (88%) carry… read more here.
Keywords: crc cells; catenin; cdh17; signalling pathway ... See more keywords
Cadherin 17 is related to recurrence and poor prognosis of cytokeratin 19-positive hepatocellular carcinoma.
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DOI: 10.3892/ol.2017.7320
Abstract: A previous study demonstrated that cytokeratin 19 (CK19) expression in hepatocellular carcinoma (HCC) is an indicator of HCC invasiveness, including lymph node metastasis (LNM), tumor infiltration/non-encapsulation and poor prognosis. The exact mechanism by which CK19… read more here.
Keywords: hcc; poor prognosis; ck19; cdh17 ... See more keywords