Strontium-modified titanium substrate promotes osteogenic differentiation of MSCs and implant osseointegration via upregulating CDH2.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical oral implants research"
DOI: 10.1111/clr.14035
Abstract: Cadherin-mediated cell-cell adhesion and signaling are critical for morphogenesis during skeletal development, but its role in the osteogenesis triggered by biomaterials is poorly understand. While our previous studies showed that strontium (Sr)-modified sand-blasted, large grit,… read more here.
Keywords: strontium modified; osseointegration; bone; mscs ... See more keywords
MicroRNA-194 regulates cell viability and apoptosis by targeting CDH2 in prostatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s169101
Abstract: Introduction Prostate cancer (PCa) is one of the most common malignancies in men. However, a lack of understanding of the mechanism underlying PCa metastasis has strongly limited the effectiveness of therapy for this disease. Thus,… read more here.
Keywords: cell viability; cdh2; apoptosis; pca ... See more keywords
Identification of a novel variant in N-cadherin associated with dilated cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.944950
Abstract: Background Dilated cardiomyopathy (DCM), which is a major cause of heart failure, is a primary cardiac muscle disease with high morbidity and mortality rates. DCM is a genetically heritable disease and more than 10 gene… read more here.
Keywords: cadherin associated; cell; adhesion; dilated cardiomyopathy ... See more keywords
Flying under the radar: CDH2 (N-cadherin), an important hub molecule in neurodevelopmental and neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.972059
Abstract: CDH2 belongs to the classic cadherin family of Ca2+-dependent cell adhesion molecules with a meticulously described dual role in cell adhesion and β-catenin signaling. During CNS development, CDH2 is involved in a wide range of… read more here.
Keywords: cdh2 cadherin; important hub; cadherin important; cdh2 ... See more keywords