Articles with "cdk2 gsk" as a keyword



Benzimidazole‐oxindole hybrids: A novel class of selective dual CDK2 and GSK‐3β inhibitors of potent anticancer activity

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Published in 2024 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202300721

Abstract: A new series of benzimidazole‐oxindole hybrids 8a–x was discovered as dual cyclin‐dependent kinase (CDK2) and glycogen synthase kinase‐3‐beta (GSK‐3β) inhibitors with potent anticancer activity. The synthesized hits displayed potent anticancer activity against national cancer institute… read more here.

Keywords: cdk2; cdk2 gsk; benzimidazole oxindole; potent anticancer ... See more keywords