CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
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DOI: 10.1038/s41467-019-12001-2
Abstract: Despite the development of adjuvant therapies, glioblastoma (GBM) patients remain incurable, thus justifying the urgent need of new therapies. CDK5 plays a critical role in GBM and is a potential target for GBM. However, the… read more here.
Keywords: trim59; cdk5 dependent; nuclear translocation; tumorigenicity ... See more keywords