CDK5RAP1 targeting NF-κB signaling pathway in human malignant melanoma A375 cell apoptosis
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DOI: 10.3892/ol.2018.7920
Abstract: Malignant melanoma is characterized by rapid deterioration, early metastasis and high mortality. Cdk5 regulatory subunit-associated protein 1 (CDK5RAP1), which catalyzes 2-methylthio (ms2) modification of mitochondrial transfer RNAs, has been reported to induce cancer cell apoptosis,… read more here.
Keywords: apoptosis; a375 cells; cdk5rap1 deficiency; signaling pathway ... See more keywords