A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022)
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DOI: 10.1080/13543776.2023.2195547
Abstract: ABSTRACT Introduction Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of serine/threonine protein kinases and participates in the regulation of the cell cycle and mRNA transcription. CDK7 is emerging as a possible… read more here.
Keywords: review; cdk7; dependent kinase; cyclin dependent ... See more keywords
Identification of CDK7 Inhibitors from Natural Sources Using Pharmacoinformatics and Molecular Dynamics Simulations
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DOI: 10.3390/biomedicines9091197
Abstract: The cyclin-dependent kinase 7 (CDK7) plays a crucial role in regulating the cell cycle and RNA polymerase-based transcription. Overexpression of this kinase is linked with various cancers in humans due to its dual involvement in… read more here.
Keywords: identification cdk7; cdk7; molecular dynamics; cdk7 inhibitors ... See more keywords