A novel 31bp deletion within the CDKL5 gene is significantly associated with growth traits in Dezhou donkey.
Sign Up to like & getrecommendations! Published in 2021 at "Animal biotechnology"
DOI: 10.1080/10495398.2021.1977653
Abstract: The discovery of molecular markers which associate with livestock economic traits is of great significance for livestock breeding. Selective analysis has found a potential correlation between CDKL5 and growth traits, but there is still a… read more here.
Keywords: significantly associated; cdkl5 gene; dezhou donkey; growth ... See more keywords
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz1214
Abstract: Abstract A significant number of X-linked genes escape from X chromosome inactivation and are associated with a distinct epigenetic signature. One epigenetic modification that strongly correlates with X-escape is reduced DNA methylation in promoter regions.… read more here.
Keywords: dna methylation; artificial escape; cdkl5 gene; escape ... See more keywords