Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors
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DOI: 10.3389/fendo.2018.00393
Abstract: The CDKN1B gene encodes for the p27Kip1 protein, firstly characterized as a cyclin dependent kinase (CDK)-inhibitor. Germline CDKN1B pathogenic variants have been described in hereditary tumors, such as multiple endocrine neoplasia (MEN)-like syndromes and familial… read more here.
Keywords: cdkn1b; luminal breast; breast cancer; cancer ... See more keywords