The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010365
Abstract: Type I interferon (IFN) has been identified in patients with Lyme disease, and its abundant expression in joint tissues of C3H mice precedes development of Lyme arthritis. Forward genetics using C3H mice with severe Lyme… read more here.
Keywords: arthritis; ifn; mice; cdkn2a gene ... See more keywords
Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1038380
Abstract: Background A feasible method to detect somatic copy number deletion (SCND) of genes is still absent to date. Methods Interstitial base-resolution deletion/fusion coordinates for CDKN2A were extracted from published articles and our whole genome sequencing… read more here.
Keywords: deletion; cdkn2a gene; quantitative multiplex; copy number ... See more keywords