Phenocopies in melanoma-prone families with germ-line CDKN2A mutations
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DOI: 10.1038/gim.2017.216
Abstract: PurposeCarriers of CDKN2A mutations have high risks of melanoma and certain other cancers. In this study we examined the occurrence of tumors among CDKN2A wild type (wt) members of melanoma-prone families with CDKN2A mutations.MethodsSwedish and… read more here.
Keywords: among cdkn2a; cdkn2a mutated; mutated families; prone families ... See more keywords
The impact of CDKN2A mutations on overall survival in pancreatic adenocarcinoma.
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DOI: 10.1200/jco.2019.37.4_suppl.278
Abstract: 278 Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a five-year survival rate of only 9%. Analyses based on tumor DNA mutations indicate the presence of specific molecular subtypes of PDAC. Tumor genomic… read more here.
Keywords: adenocarcinoma; presence; cdkn2a mutations; cdkn2a ... See more keywords
Prognostic Impact of CDKN2A Mutations Associated With Smoking and Drinking History in Japanese Digestive Cancers
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DOI: 10.21873/anticanres.17077
Abstract: Background/Aim: Organs of the digestive system are frequent sites of cancer development, and digestive tract cancers are the leading causes of death worldwide, including in Japan. Most of these cancers are associated with smoking or… read more here.
Keywords: history; smoking drinking; associated smoking; cdkn2a mutations ... See more keywords