Interference of the long noncoding RNA CDKN2B‐AS1 upregulates miR‐181a‐5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2040
Abstract: Long noncoding RNA (lncRNA) CDKN2B‐AS1 has been shown to play a crucial role in the development as well as in the prognosis of various human cancers, including cervical cancer. However, the underlying mechanisms need to… read more here.
Keywords: cervical cancer; cdkn2b; mir 181a; cdkn2b as1 ... See more keywords
DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmic Genetics"
DOI: 10.1080/13816810.2017.1413659
Abstract: ABSTRACT Purpose: Recent genome-wide association studies reported strong association of genetic variation at the CDKN2B/CDKN2B-AS1 locus on 9p21 with normal-tension glaucoma (NTG) in multiple populations. The mechanism by which this locus causes disease remains to… read more here.
Keywords: methylation; association; glaucoma; normal tension ... See more keywords
Association of a Chromosome Locus 9p21.3 CDKN2B-AS1 Variant rs4977574 with Hypertension: The TAMRISK Study.
Sign Up to like & getrecommendations! Published in 2018 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2017.0249
Abstract: AIMS Chromosome locus 9p21.3 CDKN2B antisense RNA 1 (CDKN2B-AS1) has been found to contain multiple genetic markers for coronary artery disease (CAD) by genome-wide association studies (GWAS). Of these, the association of variants rs4977574, rs10757274,… read more here.
Keywords: cdkn2b; locus 9p21; chromosome locus; hypertension ... See more keywords
CDKN2B antisense RNA 1 suppresses tumor growth in human colorectal cancer by targeting MAPK inactivator dual specificity phosphatase 1.
Sign Up to like & getrecommendations! Published in 2021 at "Carcinogenesis"
DOI: 10.1093/carcin/bgab077
Abstract: Aberrant expression of long noncoding RNA (lncRNA) CDKN2B-AS1 has been detected in human colorectal cancer (CRC). This study aimed to investigate the role of CDKN2B-AS1 and the underlying mechanism in human CRC. Gain- and loss-of-function… read more here.
Keywords: crc cells; growth; cdkn2b; cdkn2b as1 ... See more keywords
Case report: The smallest 9p21.3 microdeletion involving CDKN2A but not CDKN2B causes multiple plexiform neurofibromas
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1437093
Abstract: Chromosome 9p21.3 is a locus associated with a rare autosomal dominant cancer predisposition syndrome characterized by early-onset melanoma and a broad spectrum of neural system tumors. Two major tumor-suppressor genes, cyclin-dependent kinase inhibitor 2A and… read more here.
Keywords: plexiform neurofibromas; cdkn2b; involving cdkn2a; cdkn2a ... See more keywords
Association of Myocardial Infarction with CDKN2B Antisense RNA 1 (CDKN2B-AS1) rs1333049 Polymorphism in Slovenian Subjects with Type 2 Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13030526
Abstract: Background: We examined the role of rs1333049 polymorphism of the CDKN2B Antisense RNA 1 (CDKN2B-AS1) on the prevalence of myocardial infarction (MI) in Slovenian subjects with type 2 diabetes mellitus (T2DM). Methods: A total of… read more here.
Keywords: cdkn2b antisense; cdkn2b as1; cdkn2b; rs1333049 polymorphism ... See more keywords