Interference of the long noncoding RNA CDKN2B‐AS1 upregulates miR‐181a‐5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2040
Abstract: Long noncoding RNA (lncRNA) CDKN2B‐AS1 has been shown to play a crucial role in the development as well as in the prognosis of various human cancers, including cervical cancer. However, the underlying mechanisms need to… read more here.
Keywords: cervical cancer; cdkn2b; mir 181a; cdkn2b as1 ... See more keywords
Association between a polymorphic variant in the CDKN2B‐AS1/ANRIL gene and pancreatic cancer risk
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DOI: 10.1002/ijc.34383
Abstract: Genes carrying high‐penetrance germline mutations may also be associated with cancer susceptibility through common low‐penetrance genetic variants. To increase the knowledge on genetic pancreatic ductal adenocarcinoma (PDAC) aetiology, the common genetic variability of PDAC familial… read more here.
Keywords: as1 anril; cdkn2b as1; risk; association ... See more keywords
Deciphering the role of circulating lncRNAs: RNCR2, NEAT2, CDKN2B-AS1, and PVT1 and the possible prediction of anti-VEGF treatment outcomes in diabetic retinopathy patients
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04409-9
Abstract: Putative roles of long non-coding RNAs (lncRNAs) as indicators for diabetic retinopathy (DR) and associated complications are beginning to emerge. We aimed to evaluate a panel of circulating hyperglycemia-related lncRNAs: RNCR2, NEAT2, CDKN2B-AS1, and PVT1… read more here.
Keywords: diabetic retinopathy; rncr2 neat2; neat2 cdkn2b; as1 pvt1 ... See more keywords
Association of a Chromosome Locus 9p21.3 CDKN2B-AS1 Variant rs4977574 with Hypertension: The TAMRISK Study.
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DOI: 10.1089/gtmb.2017.0249
Abstract: AIMS Chromosome locus 9p21.3 CDKN2B antisense RNA 1 (CDKN2B-AS1) has been found to contain multiple genetic markers for coronary artery disease (CAD) by genome-wide association studies (GWAS). Of these, the association of variants rs4977574, rs10757274,… read more here.
Keywords: cdkn2b; locus 9p21; chromosome locus; hypertension ... See more keywords
CDKN2B antisense RNA 1 suppresses tumor growth in human colorectal cancer by targeting MAPK inactivator dual specificity phosphatase 1.
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DOI: 10.1093/carcin/bgab077
Abstract: Aberrant expression of long noncoding RNA (lncRNA) CDKN2B-AS1 has been detected in human colorectal cancer (CRC). This study aimed to investigate the role of CDKN2B-AS1 and the underlying mechanism in human CRC. Gain- and loss-of-function… read more here.
Keywords: crc cells; growth; cdkn2b; cdkn2b as1 ... See more keywords
Significance of lncRNA CDKN2B-AS1 in Interventional Therapy of Liver Cancer and the Mechanism under Its Participation in Tumour Cell Growth via miR-199a-5p
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2313416
Abstract: Methods Totally 34 LC patients admitted to our hospital between January 2020 and March 2021 (Obs group) and 32 healthy individuals over the same time span (Con group) were enrolled. CDKN2B-AS1 and miR-199a-5p in the… read more here.
Keywords: growth; cdkn2b as1; mir 199a; therapy ... See more keywords
lncRNA CDKN2B-AS1 Could Be an Indicator to Identify Prognosis and Status of Immune Microenvironment in Thyroid Cancer
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DOI: 10.1155/2022/4317480
Abstract: Thyroid cancer (TC) is prone to recurrence, and biomarkers for predicting progression-free interval (PFI) are poorly explored. The study investigates the predictive value and underlying biological mechanisms of lncRNA CDKN2B-AS1 in TC. Combining RNA-seq and… read more here.
Keywords: lncrna cdkn2b; immune microenvironment; as1; thyroid cancer ... See more keywords
The association between the chromosome 9p21 CDKN2B-AS1 gene variants and the lipid metabolism: A pre-diagnostic biomarker for coronary artery disease.
Sign Up to like & getrecommendations! Published in 2018 at "Anatolian journal of cardiology"
DOI: 10.14744/anatoljcardiol.2018.90907
Abstract: OBJECTIVE Recent genome-wide association studies have established that polymorphisms within CDKN2B-AS1 of chr9p21.3 locus increased susceptibility to coronary artery disease (CAD) or myocardial infarction. Common variants of CDKN2B-AS1 (including rs4977574 A>G and rs1333040 C>T) are… read more here.
Keywords: association; lipid metabolism; cad; cdkn2b as1 ... See more keywords
Association of Myocardial Infarction with CDKN2B Antisense RNA 1 (CDKN2B-AS1) rs1333049 Polymorphism in Slovenian Subjects with Type 2 Diabetes Mellitus
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DOI: 10.3390/genes13030526
Abstract: Background: We examined the role of rs1333049 polymorphism of the CDKN2B Antisense RNA 1 (CDKN2B-AS1) on the prevalence of myocardial infarction (MI) in Slovenian subjects with type 2 diabetes mellitus (T2DM). Methods: A total of… read more here.
Keywords: cdkn2b antisense; cdkn2b as1; cdkn2b; rs1333049 polymorphism ... See more keywords