PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression
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DOI: 10.7150/thno.53023
Abstract: Background: Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that symmetrically di-methylates arginine residues on both histone and non-histone protein substrates. Accumulating evidence suggests that PRMT5 exerts its oncogenic properties in a… read more here.
Keywords: prmt5; cdkn2b expression; prmt5 ezh2; crc ... See more keywords