CDKN3 as a key regulator of G2M phase in triple‐negative breast cancer: Insights from multi‐transcriptomic analysis
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DOI: 10.1002/iub.2922
Abstract: Triple‐negative breast cancer (TNBC) remains a significant global health challenge, emphasizing the need for precise identification of patients with specific therapeutic targets and those at high risk of metastasis. This study aimed to identify novel… read more here.
Keywords: cdkn3; cancer; cell cycle; analysis ... See more keywords
CDKN3 Overcomes Bladder Cancer Cisplatin Resistance via LDHA-Dependent Glycolysis Reprogramming
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DOI: 10.2147/ott.s358008
Abstract: Background Aerobic glycolysis plays an important role in bladder cancer (BLCA) progression and chemoresistance. Cyclin-dependent kinase inhibitor-3 (CDKN3), a dual-specificity protein tyrosine phosphatase, has aberrant upregulation in multiple cancer types and is associated with tumorigenesis.… read more here.
Keywords: cdkn3; glycolysis; bladder cancer; chemoresistance ... See more keywords
KLF7 promotes preadipocyte proliferation via activation of the Akt signaling pathway by Cis-regulating CDKN3
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DOI: 10.3724/abbs.2022144
Abstract: Krüppel-like transcription factor 7 (KLF7) promotes preadipocyte proliferation; however, its target gene in this process has not yet been identified. Using KLF7 ChIP-seq analysis, we previously showed that a KLF7-binding peak is present upstream of… read more here.
Keywords: proliferation via; preadipocyte proliferation; proliferation; cdkn3 ... See more keywords