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Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential

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Published in 2017 at "Neurobiology of Disease"

DOI: 10.1016/j.nbd.2016.07.009

Abstract: Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) promote the survival of midbrain dopaminergic neurons which degenerate in Parkinson's disease (PD). However, CDNF and MANF are structurally and functionally clearly distinct from… read more here.

Keywords: cdnf manf; physiological functions; unconventional neurotrophic; factors cdnf ... See more keywords