Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly
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DOI: 10.7554/elife.60351
Abstract: Holoprosencephaly (HPE), a defect in midline patterning of the forebrain and midface, arises ~1 in 250 conceptions. It is associated with predisposing mutations in the Nodal and Hedgehog (HH) pathways, with penetrance and expressivity graded… read more here.
Keywords: nodal signaling; model; cdon mutation; fetal alcohol ... See more keywords