Reconstitution of an Anti‐HER2 Antibody Paratope by Grafting Dual CDR‐Derived Peptides onto a Small Protein Scaffold
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.202000078
Abstract: Target‐binding small proteins are promising alternatives to conventional monoclonal antibodies (mAbs), offering advantages in terms of tissue penetration and manufacturing costs. Recently, a design strategy to create small proteins called fluctuation‐regulated affinity proteins (FLAPs) consisting… read more here.
Keywords: protein scaffold; dual cdr; cdr derived; cdr ... See more keywords
Spreader‐CDR system for efficient, reproducible, and frugal western blot
Sign Up to like & getrecommendations! Published in 2021 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202000380
Abstract: Efficient antibody incubation is a vital step for successful western blot. During the incubation, a thin antibody‐depleted layer is created around the blotting membrane, which limits antibody binding. Although the conventional batch shaking method is… read more here.
Keywords: spreader; incubation; antibody; western blot ... See more keywords
Composite detection rate as an upper gastrointestinal endoscopy quality measure correlating with detection of neoplasia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-021-01790-3
Abstract: Esophagogastroduodenoscopy (EGD) is commonly used diagnostic method with no widely accepted quality measure. We assessed quality indicator—composite detection rate (CDR)—consisting of detection of at least one of the following: cervical inlet patch, gastric polyp and… read more here.
Keywords: quality; detection; group; cdr ... See more keywords
Chagas disease reactivation in rheumatologic patients: association with immunosuppressive therapy and humoral response
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05581-2
Abstract: Evidence for Chagas disease reactivation (CDR) in rheumatologic patients under rheumatologic treatments (RTs) is scarce. To screen and follow-up patients with rheumatic diseases and concomitant Chagas disease under RT to detect CDR and to describe… read more here.
Keywords: cdr; disease reactivation; chagas disease; disease ... See more keywords
Bias in cervical total disc replacement trials
Sign Up to like & getrecommendations! Published in 2017 at "Current Reviews in Musculoskeletal Medicine"
DOI: 10.1007/s12178-017-9399-2
Abstract: Purpose of reviewCervical disc replacement (CDR) has emerged as a motion-preserving alternative to anterior cervical discectomy and fusion in selected cases. Despite favorable literature, CDR is not universally accepted because of concerns regarding bias in… read more here.
Keywords: replacement; literature; bias cervical; cdr ... See more keywords
Gullibility may be a warning sign of Alzheimer's disease dementia
Sign Up to like & getrecommendations! Published in 2018 at "International Psychogeriatrics"
DOI: 10.1017/s1041610218000844
Abstract: ABSTRACT Background: Theory of Mind reasoning, which plays a pivotal role in social interaction, is required to detect deception. Empirically, those with cognitive decline are vulnerable to deception. Methods: Participants were 45 healthy elderly adults… read more here.
Keywords: alzheimer disease; disease dementia; cdr; intention ... See more keywords
An interview with retired Commander (CDR) Everett Alvarez.
Sign Up to like & getrecommendations! Published in 2020 at "Psychological services"
DOI: 10.1037/ser0000470
Abstract: Mr. Everett Alvarez is a prior Navy pilot and officer who served during the Vietnam War as a Lieutenant Junior Grade (LTJG, O-2). Mr. Alvarez was the first pilot shot down, captured, and held as… read more here.
Keywords: everett alvarez; commander cdr; united states; alvarez ... See more keywords
Objective Test of Cochlear Dead Region: Electrophysiologic Approach using Acoustic Change Complex
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21754-7
Abstract: The goal of this study was to develop an objective and neurophysiologic method of identifying the presence of cochlear dead region (CDR) by combining acoustic change complex (ACC) responses with threshold-equalizing noise (TEN) test. The… read more here.
Keywords: cochlear dead; acc; dead region; acoustic change ... See more keywords
Fair distributions of carbon dioxide removal obligations and implications for effective national net-zero targets
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Research Letters"
DOI: 10.1088/1748-9326/ac1970
Abstract: Achieving net-zero emissions at the global level, as required to limit warming to 1.5 °C, means both rapid emissions reductions across all sectors as well as a scaling-up of carbon dioxide removal (CDR). As a… read more here.
Keywords: zero targets; carbon; net zero; net ... See more keywords
A biogeochemical model of mineral-based ocean alkalinity enhancement: impacts on the biological pump and ocean carbon uptake
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Research Letters"
DOI: 10.1088/1748-9326/acc9d4
Abstract: Minimizing anthropogenic climate disruption in the coming century will likely require carbon dioxide removal (CDR) from Earth’s atmosphere in addition to deep and rapid cuts to greenhouse gas emissions. Ocean alkalinity enhancement—the modification of surface… read more here.
Keywords: alkalinity; mineral; cdr; alkalinity enhancement ... See more keywords
Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy244
Abstract: Longer periods are needed to examine how biomarker changes occur relative to incident sporadic cognitive impairment. We evaluated molecular (CSF and imaging), structural, and cognitive biomarkers to predict incident cognitive impairment and examined longitudinal biomarker… read more here.
Keywords: cognitive biomarkers; cognitive impairment; cdr; incident cognitive ... See more keywords