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   Articles with "cdr1as" as a keyword



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The CDR1as/miR-7/TGFBR2 Axis Modulates EMT in Silica-Induced Pulmonary Fibrosis

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recommendations! Published in 2018 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfy221

Abstract: Silicosis is one of the typical forms of pneumoconiosis characterized by abnormal proliferation of fibroblasts and deposition of extracellular matrix. Recent findings have shown that microRNAs and circular RNAs (circRNAs) are implicated in many diseases.… read more here.

Keywords: tgfbr2; fibrosis; mir; silica ... See more keywords
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Abstract 3047: PRC2-mediated silencing of circRNACDR1asdrivesmiR-7-independent melanoma metastasis

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recommendations! Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-3047

Abstract: Circular RNAs are a novel class of non-coding RNAs with functions that remain poorly characterized in normal and pathological conditions. CDR1as is a non-canonical circRNA observed to act as a sponge for miR-7 in brain… read more here.

Keywords: melanoma; melanoma cells; metastasis; cdr1as ... See more keywords
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CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value

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recommendations! Published in 2018 at "Cancer Management and Research"

DOI: 10.2147/cmar.s178213

Abstract: Background The circular RNA (circRNA) antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as)/micro RNA-7(miR-7) signal axis has been investigated in many diseases via regulation of the target genes of miR-7, which participates in the… read more here.

Keywords: cdr1as mir; mir; value; cdr1as ... See more keywords
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Abundant Neural circRNA Cdr1as Is Not Indispensable for Retina Maintenance

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recommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.565543

Abstract: Cdr1as is the abundant circular RNA (circRNA) in human and vertebrate retinas. However, the role of Cdr1as in the retina remains unknown. In this study, we aimed to generate a Cdr1as knockout (KO) mouse model… read more here.

Keywords: circrna cdr1as; maintenance; circrna; cdr1as ... See more keywords
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Circular RNA CDR1as Alleviates Cisplatin-Based Chemoresistance by Suppressing MiR-1299 in Ovarian Cancer

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recommendations! Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2021.815448

Abstract: Cisplatin (CDDP) chemoresistance seriously affects the prognosis and survival of patients with ovarian cancer (OC). Previous research has shown that circular RNA CDR1as is biologically associated with a large number of cancers. However, the molecular… read more here.

Keywords: ovarian cancer; cdr1as; circular rna; cddp chemoresistance ... See more keywords

Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232012347

Abstract: Circular RNAs (circRNAs) are a large class of relatively stable RNA molecules that are highly expressed in animal brains. Many circRNAs have been associated with CNS disorders accompanied by an aberrant wake-sleep cycle. However, the… read more here.

Keywords: cycle; cdr1as; scn; expression ... See more keywords