Articles with "cdz173" as a keyword



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Phosphatidyl Inositol 3-Kinase (PI3K)-Inhibitor CDZ173 protects against LPS-induced osteolysis

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1021714

Abstract: A major complication of a joint replacement is prosthesis loosening caused by inflammatory osteolysis, leading to the revision of the operation. This is due to the abnormal activation of osteoclast differentiation and function caused by… read more here.

Keywords: cdz173; osteolysis; pi3k inhibitor; induced osteolysis ... See more keywords