Self‐Delivered Supramolecular Nanomedicine with Transformable Shape for Ferrocene‐Amplified Photodynamic Therapy of Breast Cancer and Bone Metastases
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202104645
Abstract: Although nanomedicines can passively target tumor through the enhanced permeability and retention (EPR) effect, their distribution and retention are limited by complex tumor microenvironment. Herein, a self‐delivery supramolecular nanoplatform with shape‐transforming capacity (Ce6‐CD/Fc‐pep‐PEG) is constructed… read more here.
Keywords: tumor; shape; ferrocene; pep peg ... See more keywords
Oxygen Self-Supply Engineering-Ferritin for the Relief of Hypoxia in Tumors and the Enhancement of Photodynamic Therapy Efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200116
Abstract: Hypoxia is a hallmark of the tumor microenvironment (TME) that promotes tumor development and metastasis. Photodynamic therapy (PDT) is a promising strategy in the treatment of tumors, but it is limited by the lack of… read more here.
Keywords: ce6 ftn; ftn; hypoxia; ce6 ... See more keywords
Catalase-like nanosystem for interlocking trimodal cancer therapy with hypoxia relief
Sign Up to like & getrecommendations! Published in 2020 at "Science China Materials"
DOI: 10.1007/s40843-020-1492-3
Abstract: Hypoxia is a hallmark of solid tumors, and it significantly impairs the overall anticancer efficacy, particularly photodynamic therapy (PDT). Herein, a catalase-like nanovesicle with near-infrared light-responsiveness, that is, platinum/gold nanoshell encapsulated chlorin e6 (Ce6)/resveratrol (Res)… read more here.
Keywords: catalase like; ce6 res; res lip; ce6 ... See more keywords
Genetically modified bacteria for targeted phototherapy of tumor.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120809
Abstract: Live attenuated bacteria have been used as target vehicles for genetic therapy of malignant carcinoma because they can be reprogrammed by following simple genetic rules and have the ability to target tumor hypoxic region. In… read more here.
Keywords: modified bacteria; genetically modified; coli; ce6 ... See more keywords
Imparting low dielectric constant and high modulus to polyimides via synergy between coupled silsesquioxanes and crown ethers
Sign Up to like & getrecommendations! Published in 2017 at "Composites Science and Technology"
DOI: 10.1016/j.compscitech.2017.02.002
Abstract: Abstract Our pilot research revealed that the dielectric constant of polyimide (PI) can be reduced and the modulus can be improved by assembling necklace-like interlocking complexes with crown ethers. Not only did we find that… read more here.
Keywords: oaprs ce6; dielectric constant; ce6; modulus ... See more keywords
Antitumor Effect of Photodynamic Therapy/Sonodynamic Therapy/Sono-Photodynamic Therapy of Chlorin e6 and Other Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00824
Abstract: Chlorin e6 (Ce6) has been extensively researched and developed as an antitumor therapy. Ce6 is a highly effective photosensitizer and sonosensitizer with promising future applications in photodynamic therapy, dynamic acoustic therapy, and combined acoustic and… read more here.
Keywords: chlorin; therapy; photodynamic therapy; antitumor effect ... See more keywords
Enhanced ROS-Boosted Phototherapy against Pancreatic Cancer via Nrf2-Mediated Stress-Defense Pathway Suppression and Ferroptosis Induction.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c22861
Abstract: In situ oxygen generation is the most common strategy to boost reactive oxygen species (ROS) for enhancing the efficacy of phototherapy in cancer, including photodynamic therapy (PDT) and photothermal therapy (PTT). However, hyperoxidation or hyperthermia… read more here.
Keywords: defense pathway; defense; ce6; stress defense ... See more keywords
Photo-Cross-Linkable Polymer Dots with Stable Sensitizer Loading and Amplified Singlet Oxygen Generation for Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.6b14325
Abstract: Photodynamic therapy (PDT) is a promising treatment modality for clinical cancer therapy. However, the therapeutic effect of PDT is strongly dependent on the property of photosensitizer. Here, we developed photo-cross-linkable semiconductor polymer dots doped with… read more here.
Keywords: photo cross; photodynamic therapy; cross linkable; ce6 ... See more keywords
Amphiphilic Silane Modified Multifunctional Nanoparticles for Magnetically Targeted Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b00647
Abstract: Efficient targeting is a major challenge in practical photodynamic therapy (PDT). Though the "enhanced permeability and retention" (EPR) effect is a widely used tumor targeting method, magnetic targeting strategy is more promising considering the issue… read more here.
Keywords: silane; photodynamic therapy; pdt; ce6 ... See more keywords
Simple and Multifunctional Natural Self-assembled Sterols with Anticancer Activity Mediated Supramolecular Photosensitizers for Enhanced Antitumor Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b07404
Abstract: Supramolecular photosensitizers based on the nano-sized drug delivery or combination therapy have been proposed as a promising strategy for cancer treatment. Herein, we screen and develop a series of multifunctional single component carrier based natural… read more here.
Keywords: supramolecular photosensitizers; anticancer activity; self; ce6 ... See more keywords
Enhanced Ferroptosis by Oxygen-Boosted Phototherapy Based on 2-in-1 Nanoplatform of Ferrous Hemoglobin for Tumor Synergistic Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.9b09426
Abstract: Photodynamic therapy combined with oxygenating strategies are widely employed in cancer treatment, however, oxygen-boosted PDT have failed to achieve an ideal effect due to the complexity, heterogeneity, and irreversible hypoxic environment generated by tumor tissues.… read more here.
Keywords: oxygen boosted; ferroptosis; pdt; ce6 ... See more keywords