Cecal Ligation and Puncture.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1488-4_1
Abstract: Cecal ligation and puncture (CLP) is referred to as the "gold standard" rodent model for abdominal sepsis. CLP creates a continuously leaking, polymicrobial infectious focus in the abdomen. The abdominal cavity is opened under general… read more here.
Keywords: clp; cecal ligation; ligation puncture; biology ... See more keywords
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-00987-2
Abstract: Sepsis is a life-threatening condition with a high rate of mortality. Unfortunately, very few therapies can improve outcomes in patients with sepsis. Butyrate, which is the most potent histone deacetylase (HDAC) inhibitor among short-chain fatty… read more here.
Keywords: sepsis; cecal ligation; butyrate; sodium butyrate ... See more keywords
Dauricine negatively regulates lipopolysaccharide- or cecal ligation and puncture-induced inflammatory response via NF-κB inactivation.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.03.018
Abstract: Acute lung injury (ALI) is a challenging clinical problem worldwide characterized by severe pulmonary inflammation. Dauricine, extracted from the root of traditional Chinese medicine Menispermum dauricum DC, is employed as anti-inflammatory herbs. In this study,… read more here.
Keywords: dauricine; ligation puncture; dauricine negatively; cecal ligation ... See more keywords
Peroxiredoxin 6 knockout aggravates cecal ligation and puncture‐induced acute lung injury
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.053
Abstract: Background: The aim of present study was to investigate the effects and mechanisms of peroxiredoxin (Prdx) 6 on cecal ligation and puncture (CLP) induced acute lung injury (ALI) in mice. Methods: The cecal of male… read more here.
Keywords: cecal ligation; ligation puncture; lung; injury ... See more keywords
Emodin attenuates acute lung injury in Cecal-ligation and puncture rats.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106626
Abstract: Acute lung injury (ALI) is a major cause of sepsis-induced acute respiratory failure. Emodin has been considered to play a protective role for acute lung edema in cecal ligation and puncture (CLP)-induced sepsis model. In… read more here.
Keywords: sepsis; cecal ligation; ligation puncture; emodin ... See more keywords
Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "Tissue barriers"
DOI: 10.1080/21688370.2021.1929787
Abstract: Endothelial barrier dysfunction (EBD) is the hallmark of Acute Respiratory Distress Syndrome (ARDS), a potentially lethal respiratory disorder associated with the COVID-19 - related deaths. Herein, we employed a cecal ligation and puncture (CLP) murine… read more here.
Keywords: sepsis; cecal ligation; ligation puncture; model sepsis ... See more keywords
Sex-Mediated Response to the Beta-Blocker Landiolol in Sepsis: An Experimental, Randomized Study
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003146
Abstract: Objectives: To investigate any gender effect of the beta-1 adrenergic blocker, landiolol, on cardiac performance and energy metabolism in septic rats, and to explore the expression of genes and proteins involved in this process. Design:… read more here.
Keywords: blocker landiolol; expression; cecal ligation; ligation puncture ... See more keywords
Use of Organ Dysfunction as A Primary Outcome Variable Following Cecal Ligation and Puncture: Recommendations for Future Studies.
Sign Up to like & getrecommendations! Published in 2019 at "Shock"
DOI: 10.1097/shk.0000000000001485
Abstract: Outcomes variables for research on sepsis have centered on mortality and changes in the host immune response. However, a recent task force (Sepsis-3) revised the definition of sepsis to "life-threatening organ dysfunction caused by a… read more here.
Keywords: sepsis; ligation puncture; organ dysfunction; human sepsis ... See more keywords
Corrigendum: Candida Administration Worsens Cecal Ligation and Puncture-Induced Sepsis in Obese Mice Through Gut Dysbiosis Enhanced Systemic Inflammation, Impact of Pathogen-Associated Molecules From Gut Translocation and Saturated Fatty Acid
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.613095
Abstract: [This corrects the article DOI: 10.3389/fimmu.2020.561652.]. read more here.
Keywords: administration worsens; ligation puncture; candida administration; cecal ligation ... See more keywords
The Severity of Acute Kidney and Lung Injuries Induced by Cecal Ligation and Puncture Is Attenuated by Menthol: Role of Proliferating Cell Nuclear Antigen and Apoptotic Markers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.904286
Abstract: Objective Sepsis-induced acute lung injury (ALI) and acute kidney injury (AKI) are major causes of mortality. Menthol is a natural compound that has anti-inflammatory and antioxidative actions. Since exaggerated inflammatory and oxidative stress are characteristics… read more here.
Keywords: sepsis; menthol; acute kidney; ligation puncture ... See more keywords
The Absence of Gasdermin D Reduces Nuclear Autophagy in a Cecal Ligation and Puncture-Induced Sepsis-Associated Encephalopathy Mouse Model
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13030478
Abstract: Sepsis-associated encephalopathy (SAE) is a common complication of sepsis, which is a life-threatening condition resulting from a dysregulated host response to infection. Pyroptosis, a pro-inflammatory mode of lytic cell death mediated by GSDMD (Gasdermin D),… read more here.
Keywords: sepsis; nuclear autophagy; associated encephalopathy; sepsis associated ... See more keywords