Cecal Slurry Injection in Neonatal and Adult Mice.
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DOI: 10.1007/978-1-0716-1488-4_4
Abstract: Studying the pathophysiology of sepsis still requires animal models, and the mouse remains the most commonly used species. Here we discuss the "cecal slurry" (CS) model of polymicrobial, peritoneal sepsis and compare and contrast it… read more here.
Keywords: sepsis; cecal slurry; adult mice; model ... See more keywords
Improved survival after induction of sepsis by cecal slurry in PD‐1 knockout murine neonates
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DOI: 10.1016/j.surg.2016.11.008
Abstract: Background. Sepsis and the ensuing immune dysfunction continue to be major contributors to neonatal morbidity and mortality. Neonatal sepsis also is associated with profound immune dysfunction. We have recently identified a role for a family… read more here.
Keywords: sepsis; improved survival; wild type; cecal slurry ... See more keywords